Corporate Snapshot
CEL-SCI Corp. ("CEL-SCI" or "the Company") develops cancer and infectious disease products that empower immune system defenses. CEL-SCI's lead product candidate is Multikine®, a non-toxic, second-generation cancer immunotherapy. The immunotherapy field recently gained momentum with the launch of Dendreon Corp.'s (DNDN-NASDAQ) Provenge®, which in April 2010 became the first FDA-approved therapeutic cancer vaccine. Provenge®, a treatment for prostate cancer, validated the possibility of harnessing the human immune system against a patient's own cancer. CEL-SCI's Multikine® immunotherapy, designated as an Orphan Drug by the FDA, is poised to enter a global Phase III trial in the second half of 2010 for advanced primary head and neck cancer. Multikine® has several novel characteristics that may differentiate it from the present generation of cancer vaccines: (1) in contrast to many autologous approaches, which must be made specific to each patient, Multikine® can be used off-the-shelf, thus large-scale manufacturing is possible; (2) Multikine® offers both active and passive immunity, indicating that no outside antigen is needed; and (3) Multikine® is administered to patients when the immune system is strongest (before surgery, radiation, or chemotherapy), which CEL-SCI has found to be an optimal time for inducing an effective anti-tumor immune response. Multikine® has been shown to kill ~50% of tumor cells before standard treatments commence. As well, it renders residual cancer cells that survive treatment more susceptible to radiation and chemotherapy.
*The Corporate Snapshot was last updated on June 21, 2010.
Latest Research
Quarterly
Update
2010-06-21
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Executive
Informational
Overview
2010-01-21
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Quarterly
Update
2009-11-05
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Quarterly
Update
2008-06-17
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Quarterly
Update
2008-01-18
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* An earlier Executive Informational Overview was published on October 31, 2007. A copy of this report can be obtained by emailing eio@crystalra.com.
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